Serious Science behind NuGlow™.
New cells form and move toward the top of your epidermis. As healthy newer cells continue to move up to the surface they replace older dead cells that rise to the surface of your skin. .
This renewal process takes about a month in mature skin, when old cells flake off, replaced by healthier new cells. The results: Skin appears visibly fresher, firmer, smoother and younger after just 4 weeks of product use.
What studies reveal:
Studies at leading Universities and Medical Research Institutes conducted by prominant dermatologists and scientists have established the effectiveness of GHK-cu tripeptide complex in supporting healthy tissue regeneration. The activities of the compound were supported by research studies showing positive effects on collagen deposition, tensile strength (elasticity), angiogenesis (blood vessel development) and SOD (antioxidation) activity. Put Simply, GHK-cu tripeptide complex aids in the natural process of forming new healthy skin cells which push damaged cells to the surface of the skin where they slough off. NuGlow's GHK-cu tripeptide formulas possess the necessary biochemical actions that can, in a morphological sense, restore skin to a younger appearance without causing skin irritation. Additionally, NuGlow's formulations tested both hypoallergenic and noncomedogenic.
Here are just some of the positive benefits studies have shown:
- Clinically proven to improve skin density and help restore skin firmness
- Clinically proven to tighten loose skin and improve skin elasticity
- Clinically proven to reduce the appearance of fine lines and wrinkles
- Powerful collagen and elastin promoter
- Promotes healthier, more youthful looking skin
- Improves smoothness and clarity
- Increases the benefits of natural tissue building processes
- Reduce photo damage and mottled hyper pigmentation
- Evens out tone, improves blotchiness and surface appearance
- Delivers the formula deep within the skin's surface
- Strongly increase keratinocyte (building block of the epidermis) proliferation in women of 50 year old range
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 NuGlow's patented formulation is combined with powerful antioxidants and nutrients to take you beyond AHA's, Vitamin C and Retinols in restoring firmer looking skin without irritation or damage to the skin. Independent studies show GHK-cu to increase skin density significantly beyond what studies indicate for oligo- peptide (Pal KTTS), the active ingredient in the best selling anti-aging products today claiming "Better than Botox?" that virtually 100% of people using NuGlow skincare products with patented breakthrough GHK-cu tripeptide technology experience a statistically significant improvement in their skin's appearance in 4 weeks. At 8 weeks, 100% of users saw their wrinkles diminish. |
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Cosmetic Skin Renewal and Aging Reversal Studies |
Study |
Result |
References |
Methods to Reverse Aging Effects in Human Skin |
Several open studies gave evidence for wrinkle reduction, blemish reduction, increased skin thickness, elasticity, and improved appearance. |
Pickart US Patents, 5,135,913 Skin treatment composition comprises GHL-CU or derivatives for improving skin health, increasing subcutaneous fat, dermal thickness and density, 5,348,943 Cosmetic and skin treatment compositions. |
Human skin renewal study |
A clinical study which compared the effect on the skin's production of collagen after using creams containing copper-peptides, vitamin C, or retinoic acid (retin-A) Twenty volunteers applied the various creams to their thighs daily for one month. New collagen production was determined by studying skin biopsy samples using immunohistological techniques.
The study found, that after one month, copper-peptides had the most significant effect on collagen production. Significant increases in collagen production were found in 70% of the persons treated with copper-peptide creams, 50% of the persons treated with the vitamin C cream, and 40% of the persons treated with retinoic acid. |
Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural study. Abdulghani A.A.; Sherr A.; Shirin S.; Solodkina G.; Tapia E.M.; Wolf.GottliebA.B.; Dermatology, UMDNJ, Robert Wood Johnson Medical School; Disease Management and Clinical Outcomes, 1998, 1:136-141. |
Human skin renewal study |
GHK-Cu containing liquid foundation tested on skin appearance, skin elasticity and epidermal thickness in an 8 week study. GHK-Cu containing liquid foundation improved skin appearance, and increased skin elasticity and epidermal thickness. |
A Clinical Evaluation of a Copper-Peptide Containing Liquid Foundation and Cream Concealer Designed for Improving Skin Condition. Appa Y, Barkovic S, Finkey M B, Neutrogena Corporation, Los Angeles, CA, Stephens, T, TJ Stephens & Associates, Inc, Dallas, TX Abstract P66, American Academy of Dermatology Meeting, February 2002 |
Reduction of Photo Damage |
GHK-Cu containing creams tested for reducing visible signs of aging and increasing skin density. GHK-Cu containing creams reduced visible signs of aging and increased skin density in 8 weeks on facial skin. |
The Effect of Tripeptide to Copper Ratio in Two Copper Peptide Creams on Photoaged Facial Skin. Leyden J, University of Pennsylvania, Philadelphia, PA, Grove, G, KGL, Inc/Skin Study Center, Broomall, PA; Barkovic S, Appa Y, Neutrogena Corporation, Los Angeles, CA; Abstract P67, American Academy of Dermatology Meeting, February 2002 |
Human skin renewal study |
GHK-Cu containing creams tested for effect on wrinkles, fine line, skin elasticity, skin density, and thickness. Placebo-controlled study, 71 females, 12 weeks. GHK-Cu containing creams reduced wrinkles and fine lines while increasing skin elasticity, skin density, and thickness. |
Skin Care Benefits of Copper Peptide Containing Facial Cream. Leyden J, University of Pennsylvania, Philadelphia, PA Stephens T, Thomas J Stephens & Associates, Inc, Dallas, TX; Finkey MB, Barkovic S, Neutrogena Corporation, Los Angeles, CA; Abstract P68, American Academy of Dermatology Meeting, February 2002 |
Human skin renewal study |
GHK-Cu containing eye creams tested on wrinkles, fine lines and eye appearance in placebo controlled study, 41 females, 12 weeks. In a second placebo controlled, 3 week, half face study, GHK-Cu was significantly better than a vitamin K cream.
GHK-Cu containing eye creams reduced wrinkles and fine lines while improving eye appearance in placebo-controlled study.
GHK-Cu was significantly better than a vitamin K cream. |
Skin Care Benefits of Copper Peptide Containing Eye Creams. Leyden J, University of Pennsylvania, Philadelphia, PA; Stephens T, Thomas J Stephens & Associates, Inc, Dallas, TX; Finkey MB, Barkovic S, Neutrogena Corporation, Los Angeles, CA; Abstract P69, American Academy of Dermatology Meeting, February 2002 |
Review of Cosmetic Studies on GHK-Cu |
A series of placebo-controlled studies found GHK-Cu skin creams to:
1. Tighten loose skin and improve elasticity
2. Improve skin density and firmness
3. Reduce fine lines and deep wrinkles
4. Improve skin clarity
5. Reduce photodamage and mottled hyperpigmentation
6. Strongly increase keratinocyte proliferation in women of 50 year old range |
Copper Peptide and Skin, M.B. Finkley, Y. Appa, S. Bhandarkar, Cosmeceuticals and Active Cosmetic, 2nd Edition (ISBN: 0-8247-4239-7), 2005, pp 549-563 |
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The NuGlow skincare system with GHK-cu tripeptide complex - holding 17 U.S. patents and 80 foreign patents - is safe, effective and provides you proven results.
Take advantage of our 60 day money back guarantee and experience the results for yourself.
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References:
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- Linder MC. Biochemistry of Copper. E. Freiden, Ed. Plenum Press. 1991.
- Schlesinger DH, et al. Growth-modulating serum tripeptide glycyl-histidyl-lysine. Experientia 33: 324. 1977.
- Fish, et al. Evaluation of glycyl-L-histidyl-L-lysine copper complex in acute wound healing. Effects in post Mohs' surgery wounds. Wounds 3: 171. 1991.
- Mulder, et al. Enhanced healing of ulcers in patients with diabetes by topical treatment with glycyl-L-histidyl-L-lysine copper. Wound Rep and Regen 2: 259. 1994.
- Maquart, et al. In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu(II) in rat experimental wounds. J Clin Invest 92: 2368. 1993.
- Schmidt, et al. The combined effects of glycyl-L-histidyl-L-lysine:copper (II) and cell tak on the healing of linear incision wounds. Wounds 6: 62. 1994.
- Raju, et al. Ceruloplasmin, copper ions, and angiogenesis. J Nat Cancer Inst 69. 1982.
- Miller, et al. Effects of glycyl-histidyl-lysyl chelated Cu (II) on ferritin dependent lipid peroxidation. Antioxidants in Therapy and Preventative Medicine. Plenum Pub Corp. 1990.
- Trachy, et al. Phototrichogram analysis of hair follicle stimulation: a pilot clinical study with a peptide-copper complex. Dermatologic Research Techniques. H. Maibach, Ed. CRC Press. 1996.
- Vogt, et al. Dry, moist, and wet skin wound repair. Ann Plas Surg 34 (5). 1995.
- Data on file ProCyte Corporation.
- Oddos T; Jumeau-Lafond A; Ries G. 2002 Feb 22-27. Requirement Of Copper And Tripeptide Glycyl-L-Histidyl-L-Lysine-Cu (GHK) Complex Formation For Collagen Synthesis Activity In Normal Human Dermal Fibroblasts. Presented at the American Academy of Dermatology 60th Annual Meeting. New Orleans, LA.
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You can order NuGlow wrinkle reduction cream and copper peptide skincare products separately or learn more about them by viewing our skincare products page. |
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